Genomic Landscape of High-Altitude Adaptation in East African Mountain Honey Bees (Apis mellifera) [15.10.25]
We are pleased to announce a recent scientific publication by researchers from the Kombiota network: “Genomic Landscape of High-Altitude Adaptation in East African Mountain Honey Bees (Apis mellifera)”

(Photo: M. Hasselmann)
This study reveals that two chromosomal inversions play a key role in the local adaptation of East African honey bees (Apis mellifera) to highland environments, influencing genes linked to behavior and oxygen use, and providing new insights into the genomic and regulatory mechanisms driving altitude adaptation.
This study is especially exciting because it uncovers the genetic and molecular basis of how honey bees have adapted to the challenging conditions of high-altitude environments. For the first time, whole genome and transcriptome analysis have been performed from samples collected in the Rwenzori Mountain National Park in Uganda. By linking specific chromosomal inversions to differences in behavior, physiology, and gene expression, this DFG funded research project, provides a glimpse into evolution in action. It bridges genomics, ecology, and evolution to reveal how subtle genetic changes can have profound effects on survival and adaptation. Beyond deepening our understanding of honey bee biology, these findings open new doors for studying how other species might respond to environmental pressures and climate change.
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